Curious about this home?

Ask anything — no agents, no pressure

Try asking

About This Home

This 0-bedroom, 0-bathroom commercial at 307 Historic Route 66 in Waynesville, MO is listed for $399,500 ($228 per sqft). Built in 1955, the home offers 1,750 sqft of living space on a 0.09 acres lot.

Agent Description

Don’t miss this rare opportunity to own a landmark property on America’s most famous highway! Ideally located along the iconic Historic Route 66 in the heart of Waynesville, just in time for the 100th anniversary celebration of Route 66. Previously home to a thriving coffee shop and restaurant, this property is perfectly suited for food service, retail, or any business looking to capture the steady flow of locals, tourists, and travelers exploring the Mother Road. The building offers high visibility, easy access, and ample parking, making it a turnkey opportunity for entrepreneurs and investors alike. Inside, you’ll find a well-maintained space with a functional kitchen layout, spacious dining area, and inviting character that reflects the nostalgic charm of Route 66.

Surrounded by local attractions, military traffic from nearby Fort Leonard Wood, and a steady stream of visitors, this location promises year-round exposure and growth potential. Whether you’re reviving its successful legacy as a coffee shop or reimagining it for your own concept, this is your chance to own a piece of Route 66 history while building your future. Remodeled in 2019, this turn key property offers the updates you are looking for, while still radiating the charm of a time not too long ago!

Key Features

  • Built in 1955
  • 0.09 acre lot

Property Details

1955

Monthly Cost Estimate

$2,137/mo

20% down · 6.5% · 30 years

Principal$289
Interest$1,731
Insurance$117

Estimates only. Actual payments may vary.

Location

307 Historic Route 66

Waynesville, MO 65583

Bell-Wyrick Sub

Property Details

Flooring

ConcreteWood

Construction

BrickConcreteStone

Heating

Heat Pump (Heating)

Cooling

Central Air

Appliances

DishwasherRangeWasherWater - Purifier

Questions & Answers

This 0-bedroom, 0-bathroom commercial at 307 Historic Route 66 is listed at $399,500 ($228/sqft). The estimated monthly payment is $1,731 based on 20% down at 6.5% interest.

Key features include: Built in 1955, 0.09 acre lot.

This property is listed by Brianne Sisti and can be reached at 5735287642 or BriSistiRealtor@gmail.com.

Similar Homes in Waynesville

View all
BS

Brianne Sisti

Agent at Jade Realty

(573) 528-7642

Listed by Jade Realty · View on Broker Site

MLS# 25076012· Source: listhub· Updated today

Copyright © 2026 Mid America Regional Information Systems, Inc. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

307 Historic Route 66, Waynesville, MO 65583

Open this listing in: