4444 Main Street, Buffalo, NY 14226

Exceptional 5-Unit Commercial Investment | Prime Main Street Location A rare and highly desirable investment opportunity in one of Western New York's most sought-after corridors. Perfectly positioned on Main Street between Williamsville and the University at Buffalo South Campus, this fully renovated mixed-use commercial property offers unmatched visibility, versatility, and income potential.

Completely updated from top to bottom, the building features five distinct income-producing units, making it an ideal asset for investors seeking strong cash flow or owner-operators looking to offset occupancy costs while building long-term equity. The lower level offers two well-designed office suites: The front unit features a spacious main area complemented by a private office or waiting room.

The rear unit includes a large open workspace, two private offices, and an optional additional room-ideal for flexible configurations. The first floor showcases two unique commercial spaces: A highly visible front unit, formerly a tattoo studio, boasts large windows, its own private entrance, and multiple additional rooms-perfect for retail, barbershop, salon, or boutique business use.

The rear unit offers a wide-open layout with a welcoming front reception area and was previously utilized as a yoga studio-ideal for fitness, wellness, or studio-based businesses. The second floor features an impressive executive office suite complete with a central hallway, multiple private offices, a dedicated waiting area, and a spacious conference room-ideal for professional services, agencies, or corporate use.

Additional highlights include: On-site parking lot approx. 9 spaces, two shared restrooms conveniently located on the main level, Prominent roadside signage offering exceptional exposure on a high-traffic Main Street corridor, Ample flexibility to suit a wide range of business types and tenant configurations Whether you're looking to fully lease al

l five units for maximum cash flow or occupy one space while generating income from the others, this property presents a compelling opportunity to secure a high-performing commercial asset in a premier location.